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I expect them to be worse than the standard thing that will get you easy pickup groups...
at doing the things basic pickup groups want
.
In MMOs that involve a lot of group play, the thing that tends to become 'Meta' is the thing that the majority of the population understands and can rely on, usually due to simplicity.
If you find a random group 'looking for Cleric' and they DON'T mean 'look just keep the tank alive and maybe cleanse some debuffs and we're good, thanks', they would probably have stuck with whoever they met that did BETTER at that.
Because it would be unrealistic to expect the others who are just 'trying to fit in and get groups' to have a specialized build ready.
If we are LUCKY, the community will come up with some simple terms to distinguish a GreatSword Wielding Mage/Fighter from a Wand Wielding Mage/Fighter because those are PROBABLY going to play very differently.
But I wouldn't personally expect the first to be worse. It's just that when you get invited, 'most people' probably aren't going to be expecting you to break out the GreatSword and start cleaving, and since you probably had to give up SOMETHING from the other option in order to do that, you might have some trouble then.
Performance wise, I wouldn't expect them to be worse, though, I'd be pretty disappointed if they couldn't make most of them work.